How harmfull is taking 300mg of tramadol a day? - Yahoo!... http://answers.yahoo.com/question/index?qid=20080811102559AAbOCBs The max dose is 400mg per day. They suggest 50-100mg every 4-6 hours.Tramadol (Ultram) 400 mg per day is maximal dose. For patients older than 75 years - not more than 300 mg per day . Recommended... lipka121 | | 0 | 248 | 0